Blar i Vitenskapelige publikasjoner (TN-IKBM) på tittel
Viser treff 78-97 av 220
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Gastrointestinal microbial community changes in Atlantic cod (Gadus morhua) exposed to crude oil
(Journal article; Peer reviewed, 2018-04)Background The expansion of offshore oil exploration increases the risk of marine species being exposed to oil pollution in currently pristine areas. The adverse effects of oil exposure through toxic properties of polycyclic ... -
Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri
(Peer reviewed; Journal article, 2021)Background The opportunistic pathogen Naegleria fowleri establishes infection in the human brain, killing almost invariably within 2 weeks. The amoeba performs piece-meal ingestion, or trogocytosis, of brain material ... -
Granular sludge bed processes in anaerobic digestion of particle-rich substrates
(Peer reviewed; Journal article, 2019-07)Granular sludge bed (GSB) anaerobic digestion (AD) is a well-established method for efficient wastewater treatment, limited, however, by the wastewater particle content. This review is carried out to investigate how and ... -
Graphene-based phenformin carriers for cancer cell treatment: a comparative study between oxidized and pegylated pristine graphene in human cells and zebrafish.
(Peer reviewed; Journal article, 2022)Graphene is an attractive choice for the development of an effective drug carrier in cancer treatment due to its high adsorption area and pH-responsive drug affinity. In combination with the highly potent metabolic drug ... -
Graphene-based phenformin carriers for cancer cell treatment: a comparative study between oxidized and pegylated pristine graphene in human cells and zebrafish†
(Peer reviewed; Journal article, 2022)Graphene is an attractive choice for the development of an effective drug carrier in cancer treatment due to its high adsorption area and pH-responsive drug affinity. In combination with the highly potent metabolic drug ... -
Green Synthesis, Characterization, Antimicrobial and Anticancer Screening of New Metal Complexes Incorporating Schiff Base
(Peer reviewed; Journal article, 2022)A Schiff base ligand of o-vanillin and 4-aminoazobenzene and its transition metal complexes of Ni(II), Co(II), Zn(II), Cu(II), Mn(II), and Zr(IV) were prepared under microwave irradiation as a green approach compared to ... -
Hepcidin analysis in pneumonia: Comparison of immunoassay and LC-MS/MS
(Peer reviewed; Journal article, 2023)Background The iron-regulatory hormone hepcidin is a promising biomarker to differentiate anaemia of inflammation from iron deficiency. Plasma hepcidin concentrations increase substantially during inflammation, and the ... -
Hepcidin predicts 5-year mortality after community-acquired pneumonia
(Peer reviewed; Journal article, 2022)Background Virtually all living organisms, including microbes and humans, depend on iron to survive and grow. During an infection, the plasma level of iron and several iron-related proteins change substantially. We ... -
Heterogeneous nutrient supply modulates root exudation and accumulation of medicinally valuable compounds in Artemisia annua and Hypericum perforatum
(Peer reviewed; Journal article, 2023)Plants have evolved complex mechanisms to adapt to nutrient-deficient environments, including stimulating lateral root proliferation into local soil patches with high nutrient content in response to heterogeneous nutrient ... -
High Cloud Point Polyvinylaminals as Non-Amide-Based Kinetic Gas Hydrate Inhibitors
(Peer reviewed; Journal article, 2020-06)In recent years, we have explored non-amide-based classes of kinetic hydrate inhibitor (KHI) polymers to determine if the same level of performance can be achieved as commercial KHI polymers, which all contain amide groups. ... -
High-Performance Kinetic Hydrate Inhibition with Poly(N-isopropyl methacrylamide) and Triisopentylamine Oxide─Surprising Concentration-Dependent Results
(Peer reviewed; Journal article, 2023)Kinetic hydrate inhibitors (KHIs) are mostly used to prevent the deposition of gas hydrates in gas and condensate production flow lines. The main component in a KHI formulation is a water-soluble polymer, blended with ... -
Highly thermostable carboxylic acid reductases generated by ancestral sequence reconstruction
(Peer reviewed; Journal article, 2019)Carboxylic acid reductases (CARs) are biocatalysts of industrial importance. Their properties, especially their poor stability, render them sub-optimal for use in a bioindustrial pipeline. Here, we employed ancestral ... -
Homeostasis at different backgrounds: The roles of overlayed feedback structures in vertebrate photoadaptation
(Peer reviewed; Journal article, 2023)We have studied the resetting behavior of eight basic integral controller motifs with respect to different but constant backgrounds. We found that the controllers split symmetrically into two classes: one class, based on ... -
Homeostatic controllers compensating for growth and perturbations
(Journal article; Peer reviewed, 2019-08)Cells and organisms have developed homeostatic mechanisms which protect them against a changing environment. How growth and homeostasis interact is still not well understood, but of increasing interest to the molecular and ... -
Homologous Recombination Deficiency Across Subtypes of Primary Breast Cancer
(Peer reviewed; Journal article, 2023)Purpose Homologous recombination deficiency (HRD) is highly prevalent in triple-negative breast cancer (TNBC) and associated with response to PARP inhibition (PARPi). Here, we studied the prevalence of HRD in non-TNBC to ... -
A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE)
(Peer reviewed; Journal article, 2022)The synthesis of four heterodimers in which the copper(I)-catalysed azide-alkyne cycloaddition was employed to connect a 1-deoxynojirimycin moiety with a benzotriazole scaffold is reported. The heterodimers were investigated ... -
Identification of Arabidopsis Protein Kinases That Harbor Functional Type 1 Peroxisomal Targeting Signals
(Peer reviewed; Journal article, 2022)Peroxisomes are eukaryotic specific organelles that perform diverse metabolic functions including fatty acid β-oxidation, reactive species metabolism, photorespiration, and responses to stress. However, the potential ... -
Identification of diagnostic and prognostic biomarkers of PD using a multiplex proteomics approach
(Peer reviewed; Journal article, 2023-10)Given the complexity of Parkinson's disease (PD), achieving acceptable diagnostic and prognostic accuracy will require the support of a panel of diverse biomarkers. We used Proximity extension assays to measure a panel of ... -
Identification of diagnostic and prognostic biomarkers of PD using a multiplex proteomics approach
(Peer reviewed; Journal article, 2023-09)Given the complexity of Parkinson's disease (PD), achieving acceptable diagnostic and prognostic accuracy will require the support of a panel of diverse biomarkers. We used Proximity extension assays to measure a panel of ... -
Impact of KRAS and BRAF mutations on treatment efficacy and survival in high-grade gastroenteropancreatic neuroendocrine neoplasms
(Peer reviewed; Journal article, 2023)High-grade gastroenteropancreatic neuroendocrine neoplasms (HG GEP-NEN) typically disseminate early. Treatment of metastatic disease has limited benefit and prognosis is generally discouraging. Data on the clinical impact ...