• Regiodivergent Synthesis of 11H-Indolo[3,2-c]quinolines and Neocryptolepine from a Common Starting Material 

      Håheim, Katja Stangeland; Lund, Bjarte Aarmo; Sydnes, Magne Olav (Peer reviewed; Journal article, 2023)
      A large number of diversely functionalized analogs of the bioactive natural products neocryptolepine and isocryptolepine have been prepared from a series of 3-bromoquinoline derivatives. The neocryptolepines were obtained ...
    • Regiospecific Photochemical Synthesis of Methylchrysenes 

      Bøhme, Thomas Andre; Egeland, Mari; Lorentzen, Marianne; Mady, Mohamed Fawzy Hamed Attia; Solbakk, Michelle F.; Sæbø, Krister Samsonsen; Jørgensen, Kåre Bredeli (Peer reviewed; Journal article, 2022-12)
      Methylated polycyclic aromatic hydrocarbons (PAHs) are suspected to be some of the toxic compounds in crude oil towards marine life and are needed as single compounds for environmental studies. 1-, 3- and 6-methylchrysene ...
    • Relationships between Isomeric Metabolism and Regioselective Toxicity of Hydroxychrysenes in Embryos of Japanese Medaka (Oryzias latipes) 

      Tanabe, Philip; Pampanin, Daniela Maria; Tiruye, Hiwot Minwuyelet; Jørgensen, Kåre Bredeli; Hammond, Rachel; Gadepalli, Rama S.; Rimoldi, John M.; Schlenk, Daniel (Peer reviewed; Journal article, 2022)
      Oxygenated polycyclic aromatic hydrocarbons (oxy-PAHs) are ubiquitous contaminants that can be formed through oxidation of parent PAHs. Our previous studies found 2-hydroxychrysene (2-OHCHR) to be significantly more toxic ...
    • Reliability and Performance of Vinyl Lactam-Based Kinetic Hydrate Inhibitor Polymers after Treatment under a Range of Conditions 

      Kelland, Malcolm Andrew; Zhang, Qian; Dirdal, Erik Gisle; Mady, Mohamed Fawzy Hamed Attia (Peer reviewed; Journal article, 2021)
      Well-known kinetic hydrate inhibitors (KHIs) such as poly(N-vinylcaprolactam) (PVCap), poly(N-vinylpyrrolidone) (PVP), and 1:1 N-vinylcaprolactam:N-vinylpyrrolidone (VCap:VP) copolymer have been subjected to a range of ...
    • Review of Nanotechnology Impacts on Oilfield Scale Management 

      Mady, Mohamed Fawzy Hamed Attia; Kelland, Malcolm Andrew (Peer reviewed; Journal article, 2020)
      Nanotechnology has grown rapidly in both research and applications over the past two decades including in the upstream petroleum industry. A recent hot area for studying nanotechnology has been oilfield scale management. ...
    • A review on energy and cost effective phase separated pretreatment of biosolids 

      Rajesh Banu, Banu; Poornima Devi, T.; Yukesh Kannah, Kannah; Kavitha, S.; Kim, Sang-Hyoun; Muñoz, Raul; Kumar, Gopalakrishnan (Peer reviewed; Journal article, 2021-06)
      Extracellular Polymeric Substances (EPS) existent in anaerobic sludge proves to be a barrier for sludge liquefaction and biomass lysis efficiency. Hence EPS deaggregation heightens the surface area for the subsequent ...
    • Review on Geopolymers as Wellbore Sealants: State of the Art Optimization for CO2 Exposure and Perspectives 

      Hajiabadi, Seyed Hasan; Khalifeh, Mahmoud; Van Noort, Reinier; Silva Santos Moreira, Paulo Henrique (Peer reviewed; Journal article, 2023-06)
      Wellbores used in underground production and storage activities, including carbon capture and storage (CCS), are typically sealed using sealants based on Ordinary Portland Cement (OPC). However, leakage along these seals ...
    • A review on occurrence and spread of antibiotic resistance in wastewaters and in wastewater treatment plants: Mechanisms and perspectives 

      Uluseker, Cansu; Kaster, Krista Michelle; Thorsen, Kristian; Basiry, Daniel; Shobana, Sutha; Jain, Monika; Kumar, Gopalakrishnan; Kommedal, Roald; Pala-Ozkok, Ilke (Peer reviewed; Journal article, 2021-10)
      This paper reviews current knowledge on sources, spread and removal mechanisms of antibiotic resistance genes (ARGs) in microbial communities of wastewaters, treatment plants and downstream recipients. Antibiotic is the ...
    • Salting-Out Assisted Liquid-Liquid Extraction for UPLC-MS/MS Determination of Thyroxine and Steroid Hormones in Human Serum and Fish Plasma 

      Urge, Alemnesh Yirda; Pampanin, Daniela Maria; Martino, Maria Elena; Knudsen, David Lausten; Brede, Cato (Peer reviewed; Journal article, 2023)
      Measuring the level of steroid and thyroxine hormones is key to understanding organism health conditions. Liquid chromatography coupled with tandem mass spectrometry has become the method of choice for such hormone analyses ...
    • Sample Preparation Strategies for Antibody-Free Quantitative Analysis of High Mobility Group Box 1 Protein 

      Kvivik, Ingeborg; Jonsson, Grete; Omdal, Roald; Brede, Cato (Peer reviewed; Journal article, 2021-06)
      Sickness behavior and fatigue are induced by cerebral mechanisms involving inflammatory cytokines. High mobility group box 1 (HMGB1) is an alarmin, and a potential key player in this process. Reliable quantification methods ...
    • Seed Amplification Assay as a Diagnostic Tool in Newly-Diagnosed Parkinson's Disease 

      Oftedal, Linn Silje Wathne; Maple-Gørdem, Jodi; Tysnes, Ole-Bjørn; Alves, Guido Werner; Lange, Johannes (Peer reviewed; Journal article, 2023)
      Seed amplification assays (SAA) are the first credible molecular assay for Parkinson’s disease (PD). However, the value of SAA to support the clinicians’ initial diagnosis of PD is not clear. In our study, we analyzed ...
    • Sensitivity analysis of a pathway with respect to fast and small temperature change 

      Zakhartsev, Maksim; Ruoff, Peter (Journal article; Peer reviewed, 2019)
      Temperature affects all enzymes simultaneously in a metabolic system. The enzyme concentration in a biochemical system can be considered as invariant under fast and small temperature change. Therefore, the total sensitivity ...
    • Solvent Synergists for Improved Kinetic Hydrate Inhibitor Performance of Poly(N-vinylcaprolactam) 

      Kelland, Malcolm Andrew; Dirdal, Erik Gisle; Ree, Lilian Helene Strand (Peer reviewed; Journal article, 2020)
      The synergetic effect of a range of different solvents on the kinetic hydrate inhibitor (KHI) performance of poly(N-vinylcaprolactam) (PVCap) has been investigated. The equipment used was a high-pressure (76 bar) rocking ...
    • Spatial analyses of immune cell infiltration in cancer: current methods and future directions. A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer 

      Page, David B; Broeckx, Glenn; Jahangir, Chowdhury Arif; Verbandt, Sara; Gupta, Rajarsi R; Thagaard, Jeppe; Khiroya, Reena; Kos, Zuzana; Abduljabbar, Khalid; Acosta Haab, Gabriela; Acs, Balazs; Akturk, Guray; Almeida, Jonas S; Alvarado-Cabrero, Isabel; Azmoudeh-Ardalan, Farid; Badve, Sunil; Baharun, Nurkhairul Bariyah; Bellolio, Enrique R; Bheemaraju, Vydehi; Blenman, Kim RM; Botinelly Mendonça Fujimoto, Luciana; Bouchmaa, Najat; Burgues, Octavio; Cheang, Maggie Chon U; Ciompi, Francesco; Cooper, Lee AD; Coosemans, An; Corredor, Germán; Dantas Portela, Flavio Luis; Deman, Frederik; Demaria, Sandra; Dudgeon, Sarah N; Elghazawy, Mahmoud; Ely, Scott; Fernandez-Martín, Claudio; Fineberg, Susan; Fox, Stephen B; Gallagher, William M; Giltnane, Jennifer M; Gnjatic, Sacha; Gonzalez-Ericsson, Paula I; Grigoriadis, Anita; Halama, Niels; Hanna, Matthew G; Harbhajanka, Aparna; Hardas, Alexandros; Hart, Steven N; Hartman, Johan; Hewitt, Stephen; Hida, Akira I; Horlings, Hugo M; Husain, Zaheed; Hytopoulos, Evangelos; Irshad, Sheeba; Janssen, Emiel; Kahila, Mohamed; Kataoka, Tatsuki R; Kawaguchi, Kosuke; Kharidehal, Durga; Khramtsov, Andrey I; Kiraz, Umay; Kirtani, Pawan; Kodach, Liudmila L; Korski, Konstanty; Kovács, Anikó; Laenkholm, Anne-Vibeke; Lang-Schwarz, Corinna; Larsimont, Denis; Lennerz, Jochen K; Lerousseau, Marvin; Li, Xiaoxian; Ly, Amy; Madabhushi, Anant; Maley, Sai K; Manur Narasimhamurthy, Vidya; Marks, Douglas K; McDonald, Elizabeth S; Mehrotra, Ravi; Michiels, Stefan; Minhas, Fayyaz ul Amir Afsar; Mittal, Shachi; Moore, David A; Mushtaq, Shamim; Nighat, Hussain; Papathomas, Thomas; Penault-Llorca, Frederique; Perera, Rashindrie D; Pinard, Christopher J; Pinto-Cardenas, Juan Carlos; Pruneri, Giancarlo; Pusztai, Lajos; Rahman, Arman; Rajpoot, Nasir Mahmood; Rapoport, Bernardo Leon; Rau, Tilman T; Reis-Filho, Jorge S; Ribeiro, Joana M; Rimm, David; Vincent-Salomon, Anne; Salto-Tellez, Manuel; Saltz, Joel; Sayed, Shahin; Siziopikou, Kalliopi P; Sotiriou, Christos; Stenzinger, Albrecht; Sughayer, Maher A; Sur, Daniel; Symmans, Fraser; Tanaka, Sunao; Taxter, Timothy; Tejpar, Sabine; Teuwen, Jonas; Thompson, E Aubrey; Tramm, Trine; Tran, William T; van der Laak, Jeroen; van Diest, Paul J; Verghese, Gregory E; Viale, Giuseppe; Vieth, Michael; Wahab, Noorul; Walter, Thomas; Waumans, Yannick; Wen, Hannah Y; Yang, Wentao; Yuan, Yinyin; Adams, Sylvia; Bartlett, John Mark Seaverns; Loibl, Sibylle; Denkert, Carsten; Savas, Peter; Loi, Sherene; Salgado, Roberto; Specht Stovgaard, Elisabeth (Peer reviewed; Journal article, 2023)
      Modern histologic imaging platforms coupled with machine learning methods have provided new opportunities to map the spatial distribution of immune cells in the tumor microenvironment. However, there exists no standardized ...
    • Spatial and temporal axes impact ecology of the gut microbiome in juvenile European lobster (Homarus gammarus) 

      Holt, Corey C.; Van der Giezen, Mark; Daniels, Carly L.; Stentiford, Grant D.; Bass, David (Peer reviewed; Journal article, 2019)
      Microbial communities within the gut can markedly impact host health and fitness. To what extent environmental influences affect the differential distribution of these microbial populations may therefore significantly ...
    • Specific PP2A Catalytic Subunits Are a Prerequisite for Positive Growth Effects in Arabidopsis Co-Cultivated with Azospirillum brasilense and Pseudomonas simiae 

      Averkina, Irina Orestovna; Paponov, Ivan; Lillo, Cathrine (Peer reviewed; Journal article, 2020-12)
      Plant growth-promoting rhizobacteria (PGPR) stimulate plant growth, but the underlying mechanism is poorly understood. In this study, we asked whether PROTEIN PHOSPHATASE 2A (PP2A), a regulatory molecular component of ...
    • Spent coffee grounds anaerobic digestion: Investigating substrate to inoculum ratio and dilute acid thermal pretreatment 

      Semaan, Georgeio; Atelge, M.R.; Dune Cayetano, Roent; Kumar, Gopalakrishnan; Kommedal, Roald (Peer reviewed; Journal article, 2022)
      Spent coffee grounds have the potential of being used in further bioprocesses to produce materials and fuels. In Norway, the relative abundance and ease of collection of this waste substrate make it a candidate for ...
    • Statistical Approaches for Dissolution Profile Comparisons of Metformin Film-Coated Tablets 

      Mitrevska, Ivana; Pejov, Ljupco; Trajkovikj, Stefan; Brezovska, Katerina; Dimitrovska, Aneta; Ugarkovic, Sonja (Peer reviewed; Journal article, 2020)
      The objective of this work was to apply several statistical approaches to profile comparison on dissolution data of Metformin immediate release film-coated tablets to assure that the developed formulation of the test product ...
    • Stochastic simulations as a tool for assessing signal fidelity in gene expression in synthetic promoter design 

      Righetti, Elena; Uluseker, Cansu; Kahramanoğulları, Ozan (Peer reviewed; Journal article, 2021-07)
      The design and development of synthetic biology applications in a workflow often involve connecting modular components. Whereas computer-aided design tools are picking up in synthetic biology as in other areas of engineering, ...
    • Stool Microbiota Diversity Analysis of Blastocystis-Positive and Blastocystis-Negative Individuals 

      Stensvold, Christen Rune; Sørland, Brede Aksdal; Berg, Rebecca P. K. D.; Andersen, Lee O’Brien; van der Giezen, Mark; Bowtell, Joanna L.; El-Badry, Ayman A.; Belkessa, Salem; Kurt, Özgür; Nielsen, Henrik Vedel (Peer reviewed; Journal article, 2022)
      Blastocystis is a unicellular eukaryote found in the gastrointestinal tract of both human and other animal hosts. The clinical significance of colonic Blastocystis colonization remains obscure. In this study, we used ...