Blar i Vitenskapelige publikasjoner (TN-IKBM) på forfatter "Grøsvik, Kristin"
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Alexeeva, M., Moen, M.N., Grøsvik, K. et al (2018) Excision of uracil from DNA by hSMUG1 includes strand incision and processing.
Moen, Marivi Nabong; Grøsvik, Kristin; Kirpekar, Finn; Tesfahun, Almaz Nigatu; Ruoff, Peter; Klungland, Arne; Bjelland, Svein (Journal article; Peer reviewed, 2018-11)Uracil arises in DNA by hydrolytic deamination of cytosine (C) and by erroneous incorporation of deoxyuridine monophosphate opposite adenine, where the former event is devastating by generation of C → thymine transitions. ... -
The escherichia coli alkA gene is activated to alleviate mutagenesis by an oxidized deoxynucleoside
Grøsvik, Kristin; Tesfahun, Almaz Nigatu; Muruzábal-Lecumberri, Izaskun; Haugland, Gyri Teien; Leiros, Ingar; Ruoff, Peter; Kvaløy, Jan Terje; Knævelsrud, Ingeborg; Ånensen, Hilde; Alexeeva, Marina; Sato, Kousuke; Matsuda, Akira; Alseth, Ingrun; Klungland, Arne; Bjelland, Svein (Peer reviewed; Journal article, 2020)The cellular methyl donor S-adenosylmethionine (SAM) and other endo/exogenous agents methylate DNA bases non-enzymatically into products interfering with replication and transcription. An important product is 3-methyladenine ...