Browsing Vitenskapelige publikasjoner (TN-IKBM) by Author "Griffiths, Gareth Wyn"
Now showing items 1-2 of 2
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Subcellular localization and therapeutic efficacy of polymeric micellar nanoparticles encapsulating bedaquiline for tuberculosis treatment in zebrafish
Bhandari, Madhavi; Soria-Carrera, Héctor; Wohlmann, Jens; Dal, Nils-Jørgen; de la Fuente, Jesús M.; Martín-Rapún, Rafael; Griffiths, Gareth Wyn; Fenaroli, Federico (Peer reviewed; Journal article, 2023)The combination drug regimens that have long been used to treat tuberculosis (TB), caused by Mycobacterium tuberculosis, are fraught with problems such as frequent administration, long duration of treatment, and harsh ... -
Π-Π interactions stabilize PeptoMicelle-based formulations of Pretomanid derivatives leading to promising therapy against tuberculosis in zebrafish and mouse models
Dal, Nils-Jørgen; Schäfer, Gabriela; Thompson, Andrew; Schmitt, Sascha; Redinger, Natalja; Alonso Rodriguez, Noelia; Johann, Kerstin; Ojong, Jessica; Wohlmann, Jens; Best, Andreas; Koynov, Kaloian; Zentel, Rudolf; Schaible, Ulrich E.; Griffiths, Gareth Wyn; Barz, Matthias; Fenaroli, Federico (Peer reviewed; Journal article, 2023)Tuberculosis is the deadliest bacterial disease globally, threatening the lives of millions every year. New antibiotic therapies that can shorten the duration of treatment, improve cure rates, and impede the development ...