Blar i Vitenskapelige publikasjoner (TN-IKBM) på emneord "VDP::Matematikk og Naturvitenskap: 400::Kjemi: 440"
Viser treff 1-20 av 55
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1,4-Dideoxy-1,4-imino‑D‑arabinitol (DAB) Analogues Possessing a Hydrazide Imide Moiety as Potent and Selective α‑Mannosidase Inhibitors
(Peer reviewed; Journal article, 2020-07)The synthesis of two polyhydroxylated pyrrolidines as 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) analogues bearing a hydrazide moiety is described. The DAB analogues act as selective and potent inhibitors of α-mannosidase ... -
Antiscaling Evaluation and Quantum Chemical Studies of Nitrogen-Free Organophosphorus Compounds for Oilfield Scale Management
(Peer reviewed; Journal article, 2021-08)Nonpolymeric aminomethylenephosphonates are widely used as powerful scale inhibitors in the petroleum industry. However, most of these inhibitors have certain drawbacks, such as low biodegradability and incompatibilities ... -
Boronic and Organic Acids as Synergists for a Poly(N-vinylcaprolactam) Kinetic Hydrate Inhibitor
(Peer reviewed; Journal article, 2021-12)A range of boronic acids have been investigated as synergists for the kinetic hydrate inhibitor (KHI) polymer, poly(N-vinylcaprolactam) (PVCap, Mw ≈ 10,000 g/mol) using high pressure rocking cells, a natural gas mixture, ... -
Cavity Size Effects on the Adsorption of CO2 on Pillar[n]arene Structures: A Density Functional Theory Study
(Peer reviewed; Journal article, 2023-08)Carbon dioxide (CO2) is the main greenhouse gas that contributes to the global warming. Therefore, CO2 adsorption is very urgent in the fight to limit global warming below 1.5 degrees Celsius. In this report, the interaction ... -
Combined Effect of Citric Acid and Polyphenol-Rich Grape Seed Extract towards Bioactive Smart Food Packaging Systems
(Peer reviewed; Journal article, 2023-07)Alginate films (2% w·v−1) were prepared with varying concentrations (5–20% w/w) of citric acid and aqueous grape seed extract (GSE) filtrate (11.66 ± 1.32 g GAE/L) using the solvent-evaporation method. Crosslinking alginate ... -
Combined Effect of Citric Acid and Polyphenol-Rich Grape Seed Extract towards Bioactive Smart Food Packaging Systems
(Peer reviewed; Journal article, 2023-07)Alginate films (2% w·v−1) were prepared with varying concentrations (5–20% w/w) of citric acid and aqueous grape seed extract (GSE) filtrate (11.66 ± 1.32 g GAE/L) using the solvent-evaporation method. Crosslinking alginate ... -
Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole−Indole Hybrids
(Peer reviewed; Journal article, 2021-04)The molecular hybridization concept has recently emerged as a powerful approach in drug discovery. A series of novel indole derivatives linked to the pyrazole moiety were designed and developed via a molecular hybridization ... -
Development of tacrine clusters as positively cooperative systems for the inhibition of acetylcholinesterase
(Peer reviewed; Journal article, 2021-07)The synthesis of four tetra-tacrine clusters where the tacrine binding units are attached to a central scaffold via linkers of variable lengths is described. The multivalent inhibition potencies for the tacrine clusters ... -
Distinct Clades of Protein Phosphatase 2A Regulatory B’/B56 Subunits Engage in Different Physiological Processes
(Peer reviewed; Journal article, 2023-07)Protein phosphatase 2A (PP2A) is a strongly conserved and major protein phosphatase in all eukaryotes. The canonical PP2A complex consists of a catalytic (C), scaffolding (A), and regulatory (B) subunit. Plants have three ... -
DNA damage and health effects in juvenile haddock (Melanogrammus aeglefinus) exposed to PAHs associated with oil-polluted sediment or produced water
(Peer reviewed; Journal article, 2020)The research objective was to study the presence of DNA damages in haddock exposed to petrogenic or pyrogenic polyaromatic hydrocarbons (PAHs) from different sources: 1) extracts of oil produced water (PW), dominated by ... -
DOPA Homeostasis by Dopamine: A Control-Theoretic View
(Peer reviewed; Journal article, 2021-11)Dopamine (DA) is an important signal mediator in the brain as well as in the periphery. The term “dopamine homeostasis” occasionally found in the literature refers to the fact that abnormal DA levels can be associated with ... -
Environmentally Friendly Phosphonated Polyetheramine Scale Inhibitors - Excellent Calcium Compatibility for Oilfield Applications
(Peer reviewed; Journal article, 2020-05)Scaling is one of the most frequently stated problems in the oil industry, and scale inhibitors (SIs) are applied to prevent its formation. Organophosphonates are well-known types of SIs, particularly useful for squeeze ... -
Evaluation of photodegradable chitin synthetase inhibitors for the treatment of salmon lice (Lepeophtheirus salmonis)
(Peer reviewed; Journal article, 2023)Some photolabile ethanolamine analogues of the chitin synthetase inhibitors diflubenzuron, teflubenzuron, and lufenuron were tested for activity as anti-lice compounds towards salmon lice (Lepeophtheirus salmonis). Two ... -
Exploring Modified Alendronic Acid as a New Inhibitor for Calcium-Based Oilfield Scales
(Peer reviewed; Journal article, 2022-02)Organophosphorus compounds are well known as oilfield scale inhibitors. Earlier work showed that a series of new and well-known bone-targeting drugs incorporating non-toxic bisphosphonates (BPs) (PO3H2–C–PO3H2) gave good ... -
Field test investigation of the performance of corrosion inhibitors: a case study
(Peer reviewed; Journal article, 2021-09)Corrosion is considered one of the major problems that affect flow assurance during hydrocarbon production. This irreversible phenomenon has the ability to cause serious material failure in the oil and gas industry. ... -
Graphene-based phenformin carriers for cancer cell treatment: a comparative study between oxidized and pegylated pristine graphene in human cells and zebrafish.
(Peer reviewed; Journal article, 2022)Graphene is an attractive choice for the development of an effective drug carrier in cancer treatment due to its high adsorption area and pH-responsive drug affinity. In combination with the highly potent metabolic drug ... -
Graphene-based phenformin carriers for cancer cell treatment: a comparative study between oxidized and pegylated pristine graphene in human cells and zebrafish†
(Peer reviewed; Journal article, 2022)Graphene is an attractive choice for the development of an effective drug carrier in cancer treatment due to its high adsorption area and pH-responsive drug affinity. In combination with the highly potent metabolic drug ... -
High Cloud Point Polyvinylaminals as Non-Amide-Based Kinetic Gas Hydrate Inhibitors
(Peer reviewed; Journal article, 2020-06)In recent years, we have explored non-amide-based classes of kinetic hydrate inhibitor (KHI) polymers to determine if the same level of performance can be achieved as commercial KHI polymers, which all contain amide groups. ... -
High-Performance Kinetic Hydrate Inhibition with Poly(N-isopropyl methacrylamide) and Triisopentylamine Oxide─Surprising Concentration-Dependent Results
(Peer reviewed; Journal article, 2023)Kinetic hydrate inhibitors (KHIs) are mostly used to prevent the deposition of gas hydrates in gas and condensate production flow lines. The main component in a KHI formulation is a water-soluble polymer, blended with ... -
A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE)
(Peer reviewed; Journal article, 2022)The synthesis of four heterodimers in which the copper(I)-catalysed azide-alkyne cycloaddition was employed to connect a 1-deoxynojirimycin moiety with a benzotriazole scaffold is reported. The heterodimers were investigated ...