Blar i Vitenskapelige publikasjoner (TN-IKBM) på emneord "kreft"
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Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole−Indole Hybrids
(Peer reviewed; Journal article, 2021-04)The molecular hybridization concept has recently emerged as a powerful approach in drug discovery. A series of novel indole derivatives linked to the pyrazole moiety were designed and developed via a molecular hybridization ... -
Graphene-based phenformin carriers for cancer cell treatment: a comparative study between oxidized and pegylated pristine graphene in human cells and zebrafish.
(Peer reviewed; Journal article, 2022)Graphene is an attractive choice for the development of an effective drug carrier in cancer treatment due to its high adsorption area and pH-responsive drug affinity. In combination with the highly potent metabolic drug ... -
Graphene-based phenformin carriers for cancer cell treatment: a comparative study between oxidized and pegylated pristine graphene in human cells and zebrafish†
(Peer reviewed; Journal article, 2022)Graphene is an attractive choice for the development of an effective drug carrier in cancer treatment due to its high adsorption area and pH-responsive drug affinity. In combination with the highly potent metabolic drug ... -
In silico investigations of intratumoral heterogeneous interstitial fluid pressure
(Peer reviewed; Journal article, 2021-06)Recent preclinical studies have shown that interstitial fluid pressure (IFP) within tumors can be heterogeneous Andersen et al. (2019). In that study tumors of two xenograft models, respectively, HL-16 cervical carcinoma ... -
Modeling 3D cancer growth and extracellular matrix properties in vitro
(Master thesis, 2018-08-15)Background: Cancer can be defined as loss of normal behavior of cellular components thus losing tissue organization and giving rise to a tumor microenvironment (TME). Increased matrix stiffness, strain and elevated ... -
Prognostic value and reproducibility of different microscopic characteristics in the WHO grading systems for pTa and pT1 urinary bladder urothelial carcinomas
(Peer reviewed; Journal article, 2019-08)Background: European treatment guidelines for pTa and pT1 urinary bladder urothelial carcinoma depend highly on stage and WHO-grade. Both the WHO73 and the WHO04 grading systems show some intra- and interobserver variability. ...