Blar i Vitenskapelige publikasjoner (TN-IKBM) på dokumenttype "Journal article"
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1,4-Dideoxy-1,4-imino‑D‑arabinitol (DAB) Analogues Possessing a Hydrazide Imide Moiety as Potent and Selective α‑Mannosidase Inhibitors
(Peer reviewed; Journal article, 2020-07)The synthesis of two polyhydroxylated pyrrolidines as 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) analogues bearing a hydrazide moiety is described. The DAB analogues act as selective and potent inhibitors of α-mannosidase ... -
5-Methyl-3-vinyl-2-oxazolidinone-Investigations of a New Monomer for Kinetic Hydrate Inhibitor Polymers
(Peer reviewed; Journal article, 2022)Kinetic hydrate inhibitors (KHIs) are polymers used in a chemical method to prevent gas hydrate plugging of oil and gas production flow lines. The main ingredient in a KHI formulation is one or more water-soluble amphiphilic ... -
Advances in the Study of Gas Hydrates by Dielectric Spectroscopy
(Peer reviewed; Journal article, 2021)The influence of kinetic hydrate inhibitors on the process of natural gas hydrate nucleation was studied using the method of dielectric spectroscopy. The processes of gas hydrate formation and decomposition were monitored ... -
Alexeeva, M., Moen, M.N., Grøsvik, K. et al (2018) Excision of uracil from DNA by hSMUG1 includes strand incision and processing.
(Journal article; Peer reviewed, 2018-11)Uracil arises in DNA by hydrolytic deamination of cytosine (C) and by erroneous incorporation of deoxyuridine monophosphate opposite adenine, where the former event is devastating by generation of C → thymine transitions. ... -
Alkyl-phenanthrenes in early life stage fish: differential toxicity in Atlantic haddock (Melanogrammus aeglefinus) embryos
(Peer reviewed; Journal article, 2023)Tricyclic polycyclic aromatic hydrocarbons (PAHs) are believed to be the primary toxic components of crude oil. Such compounds including phenanthrene are known to have direct effects on cardiac tissue, which lead to ... -
Alleviation of C⋅C Mismatches in DNA by the Escherichia coli Fpg Protein
(Peer reviewed; Journal article, 2021-06)DNA polymerase III mis-insertion may, where not corrected by its 3′→ 5′ exonuclease or the mismatch repair (MMR) function, result in all possible non-cognate base pairs in DNA generating base substitutions. The most ... -
Altered transcriptome-proteome coupling indicates aberrant proteostasis in Parkinson's disease
(Peer reviewed; Journal article, 2023)Aberrant proteostasis is thought to be implicated in Parkinson’s disease (PD), but patient-derived evidence is scant. We hypothesized that impaired proteostasis is reflected as altered transcriptome-proteome correlation ... -
Alternative Lactam-Based Kinetic Hydrate Inhibitors - Investigation of Polymers of 2‑Methacrylamido-caprolactam
(Peer reviewed; Journal article, 2022)Kinetic hydrate inhibitors (KHIs), such as poly(N-vinylcaprolactam) (PVCap) and related copolymers, are a well-known method to help combat gas hydrate formation in oil and gas field production flow lines. The caprolactam ... -
An amplified derepression controller with multisite inhibition and positive feedback
(Peer reviewed; Journal article, 2021-03)How organisms are able to maintain robust homeostasis has in recent years received increased attention by the use of combined control engineering and kinetic concepts, which led to the discovery of robust controller motifs. ... -
Anaerobic Fungi: Past, Present, and Future
(Peer reviewed; Journal article, 2020-10)Anaerobic fungi (AF) play an essential role in feed conversion due to their potent fiber degrading enzymes and invasive growth. Much has been learned about this unusual fungal phylum since the paradigm shifting work of ... -
Antiscaling Evaluation and Quantum Chemical Studies of Nitrogen-Free Organophosphorus Compounds for Oilfield Scale Management
(Peer reviewed; Journal article, 2021-08)Nonpolymeric aminomethylenephosphonates are widely used as powerful scale inhibitors in the petroleum industry. However, most of these inhibitors have certain drawbacks, such as low biodegradability and incompatibilities ... -
The Asgard Archaeal-Unique Contribution to Protein Families of the Eukaryotic Common Ancestor Was 0.3%
(Peer reviewed; Journal article, 2021-04)The identification of the asgard archaea has fueled speculations regarding the nature of the archaeal host in eukaryogenesis and its level of complexity prior to endosymbiosis. Here, we analyzed the coding capacity of 150 ... -
Association of CSF Glucocerebrosidase Activity With the Risk of Incident Dementia in Patients With Parkinson Disease
(Peer reviewed; Journal article, 2022)Background and Objectives Variations in the glucocerebrosidase gene (GBA) are common risk factors for Parkinson disease (PD) and dementia in PD (PDD) and cause a reduction in the activity of the lysosomal enzyme ... -
Association of GBA Genotype With Motor and Functional Decline in Patients With Newly Diagnosed Parkinson Disease.
(Peer reviewed; Journal article, 2020-12)Objective To establish the significance of glucocerebrosidase gene (GBA) carrier status on motor impairment in a large cohort of patients with incident Parkinson disease (PD). Methods Three European population-based ... -
Association of SNCA Parkinson's Disease Risk Polymorphisms With Disease Progression in Newly Diagnosed Patients
(Peer reviewed; Journal article, 2021-02)Objectives: To evaluate the impact of SNCA polymorphisms originally identified as risk factors for Parkinson's disease (PD) on the clinical presentation and progression of the disease in a large cohort of population-based ... -
Atropisomerism in Tertiary Biaryl 2-Amides: A Study of Ar-CO and Ar-Ar? Rotational Barriers
(Peer reviewed; Journal article, 2017)A rotational barrier study was performed on eight tertiary biaryl 2-amides using variable temperature (VT) NMR and exchange (EXSY) spectroscopy experiments. Seven out of the eight 2-amido-2′-methylbiphenyls with additional ... -
Bioaccumulation potential of the tricyclic antidepressant amitriptyline in a marine Polychaete, Nereis virens
(Peer reviewed; Journal article, 2022)The continual discharge of pharmaceuticals from wastewater treatment plants (WWTPs) into the marine environment, even at concentrations as low as ng/L, can exceed levels that induce sublethal effects to aquatic organisms. ... -
Bioeconomic evaluation of extended season and year-round tomato production in Norway using supplemental light
(Peer reviewed; Journal article, 2022)CONTEXT For high latitude countries like Norway, one of the biggest challenges associated with greenhouse production is the limited availability of natural light and heat, particularly in winters. This can be addressed ... -
Biohydrogen production from industrial wastewater: An overview
(Peer reviewed; Journal article, 2019-09)Biohydrogen production from industrial wastewater has been a focus of interest in recent years. The in depth knowledge in lab scale parameters and emerging strategies are needed to be investigated in order to implement the ... -
Boronic and Organic Acids as Synergists for a Poly(N-vinylcaprolactam) Kinetic Hydrate Inhibitor
(Peer reviewed; Journal article, 2021-12)A range of boronic acids have been investigated as synergists for the kinetic hydrate inhibitor (KHI) polymer, poly(N-vinylcaprolactam) (PVCap, Mw ≈ 10,000 g/mol) using high pressure rocking cells, a natural gas mixture, ...