• Assessing short-term risk of ischemic stroke in relation to all prescribed medications 

      Janszky, Imre; Vardaxis, Ioannis; Lindqvist, Bo Henry; Horn, Jens; Brumpton, Ben Michael; Strand, Linn Beate; Bakken, Inger Johanne Landsjøåsen; Alsnes, Ingvild Vatten; Romundstad, Pål Richard; Ljung, Rickard; Mukamal, Kenneth J.; Sen, Abhijit (Peer reviewed; Journal article, 2021-11)
      We examined the short-term risk of stroke associated with drugs prescribed in Norway or Sweden in a comprehensive, hypothesis-free manner using comprehensive nation-wide data. We identified 27,680 and 92,561 cases with a ...
    • Fatigue: a frequent and biologically based phenomenon in newly diagnosed celiac disease 

      Skjellerudsveen, Berit Mære; Omdal, Roald; Hetta, Anne Kristine; Kvaløy, Jan Terje; Aabakken, Lars; Skoie, Inger Marie; Grimstad, Tore Bjørn (Peer reviewed; Journal article, 2022)
      Fatigue is increasingly recognized as a major complaint in patients with chronic inflammatory and autoimmune diseases. Although fatigue is assumed to represent a significant problem in celiac disease, existing knowledge ...
    • Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells 

      Alhourani, Abdelnour H.; Tidwell, Tia R.; Bokil, Ansooya Avinash; Røsland, Gro V.; Tronstad, Karl Johan; Søreide, Kjetil; Hagland, Hanne R. (Peer reviewed; Journal article, 2021-05)
      Cancer cells exhibit altered metabolism, a phenomenon described a century ago by Otto Warburg. However, metabolic drug targeting is considered an underutilized and poorly understood area of cancer therapy. Metformin, a ...
    • Predicting an unstable tear film through artificial intelligence 

      Fineide, Fredrik; Storås, Andrea; Chen, Xiangjun; Magnø, Morten Schjerven; Yazidi, Anis; Riegler, Michael; Utheim, Tor Paaske (Peer reviewed; Journal article, 2022)
      Dry eye disease is one of the most common ophthalmological complaints and is defined by a loss of tear film homeostasis. Establishing a diagnosis can be time-consuming, resource demanding and unpleasant for the patient. ...
    • Validation and assessment of preanalytical factors of a fluorometric in vitro assay for glucocerebrosidase activity in human cerebrospinal fluid 

      Oftedal, Linn; Maple-Grødem, Jodi; Førland, Marthe Gurine; Alves, Guido Werner; Lange, Johannes (Peer reviewed; Journal article, 2020-12)
      Lysosomal dysfunction is an emerging feature in the pathology of Parkinson’s disease and Dementia with Lewy bodies. Mutations in the GBA gene, encoding the enzyme Glucocerebrosidase (GCase), have been identified as a genetic ...
    • A wearable microwave instrument can detect and monitor traumatic abdominal injuries in a porcine model 

      Candefjord, Stefan; Nguyen, Linh; Buendia, Ruben; Oropeza-Moe, Marianne; Andersen, Nina Gjerde; Fhager, Andreas; Persson, Mikael; Elam, Mikael; Oveland, Nils Petter (Peer reviewed; Journal article, 2021-12)
      Abdominal injury is a frequent cause of death for trauma patients, and early recognition is essential to limit fatalities. There is a need for a wearable sensor system for prehospital settings that can detect and monitor ...