Blar i Studentoppgaver (TN-IKBM) på forfatter "Lorentsen, Celine"
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Replacing Pro240 with Gly in hSMUG1 increases uracil excision in R-loop but abolish 5-hydroxymethyluracil excision in ssDNA
Lorentsen, Celine (Master thesis, 2021)Deamination and oxidation of pyrimidines are two major spontaneously damaging events in DNA. The DNA glycosylase SMUG1 initiates repair of deaminated or oxidized bases by breaking the glycosidic bond between the damaged ...