Blar i Studentoppgaver (TN-IKBM) på emneord "biologisk kjemi"
Viser treff 1-20 av 44
-
Alpha-synuclein biomarkers of Parkinson's disease risk and heterogeneity
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020-06)Parkinson’s disease (PD) is the second most common neurodegenerative disease and is the world’s fastest growing neurological disorder. PD is a motor disease, but many patients experience a range of non-motor features, ... -
Anomeric O-Alkylation as a Diastereoselective Glycosylation Method
(Masteroppgave/UIS-TN-IKBM/2018;, Master thesis, 2018-06)After the Biolink group’s first full synthesis of the anthocyanins cyanidin and delphinidin in which the best results at the time were produced by anomeric O-alkylation of glucose. The Biolink research group was interested ... -
Can gut microbial community changes in Atlantic cod be used as biomarker of water pollution?
(Masteroppgave/UIS-TN-IKBM/2019;, Master thesis, 2019-06-15)The gut microbiome of juvenile Atlantic cod (Gadus morhua) was studied to evaluate changes related to the exposure of dispersed crude oil and find potential biomarker of exposures. Fish was exposed to dispersed crude oil ... -
Characterization of antimicrobial resistance in Norwegian blood culture isolates of Klebsiella pneumoniae using whole genome sequencing.
(Masteroppgave/UIS-TN-IKBM/2019;, Master thesis, 2019-06)Antimicrobial drugs are used to treat and prevent infections caused by microorganisms. For decades, they have saved millions of lives, treated diseases and reduced pain. However, when exposed to antimicrobial drugs, ... -
Characterization of Exosomes and Synthesized Exosome-Based Liposomes to Establish a Drug Delivery Scheme for the Treatment of Epilepsy.
(Masteroppgave/UIS-TN-IKBM/2019;, Master thesis, 2019-06-14)Epilepsy is one of the most prevalent, chronic, critical neurological diseases. Due to the ability of the blood-brain barrier (BBB) to prevent the entry of drugs into the brain, pharmaceutical treatment of central nervous ... -
Characterization of Norwegian blood culture isolates of Klebsiella pneumoniae using whole genome sequencing
(Masteroppgave/UIS-TN-IKBM/2018;, Master thesis, 2018-06)The increasing trend of antimicrobial resistance (AMR) has been acknowledged by the world health organization (WHO) as an urgent threat to public health. Especially the development of multi drug resistant (MDR) Gram-negative ... -
Contents of organic acids in tomato fruits as a function of light and nutrition
(Masteroppgave/UIS-TN-IKBM/2019;, Master thesis, 2019-06-10)Tomato (Solanum lycopersicum) is one of the most consumed vegetables in the world. It is a source of antioxidants, minerals and vitamins, and has many beneficial effects on health. In the last decades, the taste properties ... -
Culture-dependent versus Culture-independent Methods for Quantifying Sulphate-Reducing Bacteria in Injection and Produced Water from the Greater Ekofisk Area
(Masteroppgave/UIS-TN-IKBM/2018;, Master thesis, 2018-05-26)Planktonic and sessile bacteria, in particular sulphate-reducing bacteria (SRB), in the petroleum industry can be damaging to top-side facilities, pipelines and reservoirs. Development of microbial influenced corrosion ... -
Detection and quantification of pharmaceuticals in sediment, seawater, and wastewater treatment plant samples
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020-07-15)Active pharmaceutical ingredients (APIs) are increasingly occurring in nature. Their presence is posing a concern about antibiotic resistance in bacteria and other effects on the ecosystem, which are not yet fully understood. ... -
Detection of Nrf2 in peripheral blood mononuclear cells: comparison and application of two methods
(Masteroppgave/UIS-TN-IKBM/2018;, Master thesis, 2018-11-01)Protein nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that regulates expression of numerous proteins. These proteins protect cells against oxidative stress and reinstate cellular homeostasis. ... -
Development of a portable surface plasmon resonance based genosensor for the detection of obligate hydrocarbon degrading bacteria in the marine environment
(Masteroppgave/UIS-TN-IKBM/2019;, Master thesis, 2019-06-01)This study aimed at developing a genosensor that could be implemented in the Environmental Sample Processor (ESP) based on surface plasmon resonance (SPR) to detect obligate hydrocarbonoclastic bacteria (OHCB) that can be ... -
Development of LC-MS/MS method for analysing immunosuppressants in whole blood for the purpose of TDM, with the novel application of SALLE in the sample preparation
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020-07-06)The laboratory for Medical Biochemistry at Stavanger University Hospital (SUS) needed a new method for analysing tacrolimus, sirolimus, everolimus and cyclosporin A. A method was developed using the analytical principles ... -
Dysfunction of Protein Homeostasis: Factors in uencing the Formation of alpha - Synuclein (Lewy Bodies) in Arabidopsis thaliana plants
(Masteroppgave/UIS-TN-IKBM/2019;, Master thesis, 2019-06-15)BACKGROUND:Protein homeostasis or proteostasis under the conscious control of a network of proteins including chaperones, transporters, ubiquitin-dependent proteasome control the proper expression, folding, translocation ... -
Effect of metformin and phenformin in acute myeloid leukemia cell lines MOLM-13 and HL-60
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020-07)Cancer is a large group of diseases and a second leading cause of death globally with an estimated 9.6 million death in 2018 according to World Health Organization (WHO). It is an abnormal and uncontrollably growth of cells ... -
Effects of protein enrichment in texture modified and minced fish products
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020-06-15)The aim of this thesis was to develop two protein enriched products based on haddock and silver smelt, reaching the level of total protein in the utilized fish raw material. Both products were enriched by whey protein ... -
Entamoeba invadens; a study about the role of PLD1 and PLD2 in encystation
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020-12)One of the most common problem in the developing world is infectious diseases caused by poor living conditions and one such condition is called amoebiasis. The causative agent of which is Entamoeba histolytica; a ... -
Exploring Analytical Methods for Quality Control and Accurate Quantification of Major Biologically Active Components in Astragalus Radix
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020)Abstract Introduction Over the past decade, the worldwide consumption and sales of Traditional Chinese Medicine (TCM) herbs have grown enormously. Astragalus Radix (Chinese: Huang qi) (AR), the dried root of Astragalus ... -
Forekomst av Listeria monocytogenes i et matfiskanlegg i Hardangerfjorden
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020-06-15)I denne masteroppgaven er forekomsten av bakterien Listeria monocytogenes undersøkt i et oppdrettsanlegg for atlantisk laks (Salmo salar). Endringer i forekomsten ble observert for å undersøke tilstedeværelse og mulige ... -
Growth and inactivation of Bacillus pumilus with heat and high-pressure processing
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020-06-15)The main objective of this study was to obtain knowledge about Bacillus pumilus B367 with relevance to food safety and investigate if B. pumilus B367 would be inactivated at lower temperatures for shorter time by applying ... -
Homeostasis by depression kinetics with multisite inhibition and positive feedback
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020)In order to survive all living organisms must, to some extent, be able to adapt to the changes in environment.In recent years there have been proposed different controller motifs that are used to explain how does the ...