• Salting-Out Assisted Liquid-Liquid Extraction for UPLC-MS/MS Determination of Thyroxine and Steroid Hormones in Human Serum and Fish Plasma 

      Urge, Alemnesh Yirda; Pampanin, Daniela Maria; Martino, Maria Elena; Knudsen, David Lausten; Brede, Cato (Peer reviewed; Journal article, 2023)
      Measuring the level of steroid and thyroxine hormones is key to understanding organism health conditions. Liquid chromatography coupled with tandem mass spectrometry has become the method of choice for such hormone analyses ...
    • Sample Preparation Strategies for Antibody-Free Quantitative Analysis of High Mobility Group Box 1 Protein 

      Kvivik, Ingeborg; Jonsson, Grete; Omdal, Roald; Brede, Cato (Peer reviewed; Journal article, 2021-06)
      Sickness behavior and fatigue are induced by cerebral mechanisms involving inflammatory cytokines. High mobility group box 1 (HMGB1) is an alarmin, and a potential key player in this process. Reliable quantification methods ...
    • Seed Amplification Assay as a Diagnostic Tool in Newly-Diagnosed Parkinson's Disease 

      Oftedal, Linn Silje Wathne; Maple-Gørdem, Jodi; Tysnes, Ole-Bjørn; Alves, Guido Werner; Lange, Johannes (Peer reviewed; Journal article, 2023)
      Seed amplification assays (SAA) are the first credible molecular assay for Parkinson’s disease (PD). However, the value of SAA to support the clinicians’ initial diagnosis of PD is not clear. In our study, we analyzed ...
    • Sensitivity analysis of a pathway with respect to fast and small temperature change 

      Zakhartsev, Maksim; Ruoff, Peter (Journal article; Peer reviewed, 2019)
      Temperature affects all enzymes simultaneously in a metabolic system. The enzyme concentration in a biochemical system can be considered as invariant under fast and small temperature change. Therefore, the total sensitivity ...
    • Solvent Synergists for Improved Kinetic Hydrate Inhibitor Performance of Poly(N-vinylcaprolactam) 

      Kelland, Malcolm Andrew; Dirdal, Erik Gisle; Ree, Lilian Helene Strand (Peer reviewed; Journal article, 2020)
      The synergetic effect of a range of different solvents on the kinetic hydrate inhibitor (KHI) performance of poly(N-vinylcaprolactam) (PVCap) has been investigated. The equipment used was a high-pressure (76 bar) rocking ...
    • Spatial analyses of immune cell infiltration in cancer: current methods and future directions. A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer 

      Page, David B; Broeckx, Glenn; Jahangir, Chowdhury Arif; Verbandt, Sara; Gupta, Rajarsi R; Thagaard, Jeppe; Khiroya, Reena; Kos, Zuzana; Abduljabbar, Khalid; Acosta Haab, Gabriela; Acs, Balazs; Akturk, Guray; Almeida, Jonas S; Alvarado-Cabrero, Isabel; Azmoudeh-Ardalan, Farid; Badve, Sunil; Baharun, Nurkhairul Bariyah; Bellolio, Enrique R; Bheemaraju, Vydehi; Blenman, Kim RM; Botinelly Mendonça Fujimoto, Luciana; Bouchmaa, Najat; Burgues, Octavio; Cheang, Maggie Chon U; Ciompi, Francesco; Cooper, Lee AD; Coosemans, An; Corredor, Germán; Dantas Portela, Flavio Luis; Deman, Frederik; Demaria, Sandra; Dudgeon, Sarah N; Elghazawy, Mahmoud; Ely, Scott; Fernandez-Martín, Claudio; Fineberg, Susan; Fox, Stephen B; Gallagher, William M; Giltnane, Jennifer M; Gnjatic, Sacha; Gonzalez-Ericsson, Paula I; Grigoriadis, Anita; Halama, Niels; Hanna, Matthew G; Harbhajanka, Aparna; Hardas, Alexandros; Hart, Steven N; Hartman, Johan; Hewitt, Stephen; Hida, Akira I; Horlings, Hugo M; Husain, Zaheed; Hytopoulos, Evangelos; Irshad, Sheeba; Janssen, Emiel; Kahila, Mohamed; Kataoka, Tatsuki R; Kawaguchi, Kosuke; Kharidehal, Durga; Khramtsov, Andrey I; Kiraz, Umay; Kirtani, Pawan; Kodach, Liudmila L; Korski, Konstanty; Kovács, Anikó; Laenkholm, Anne-Vibeke; Lang-Schwarz, Corinna; Larsimont, Denis; Lennerz, Jochen K; Lerousseau, Marvin; Li, Xiaoxian; Ly, Amy; Madabhushi, Anant; Maley, Sai K; Manur Narasimhamurthy, Vidya; Marks, Douglas K; McDonald, Elizabeth S; Mehrotra, Ravi; Michiels, Stefan; Minhas, Fayyaz ul Amir Afsar; Mittal, Shachi; Moore, David A; Mushtaq, Shamim; Nighat, Hussain; Papathomas, Thomas; Penault-Llorca, Frederique; Perera, Rashindrie D; Pinard, Christopher J; Pinto-Cardenas, Juan Carlos; Pruneri, Giancarlo; Pusztai, Lajos; Rahman, Arman; Rajpoot, Nasir Mahmood; Rapoport, Bernardo Leon; Rau, Tilman T; Reis-Filho, Jorge S; Ribeiro, Joana M; Rimm, David; Vincent-Salomon, Anne; Salto-Tellez, Manuel; Saltz, Joel; Sayed, Shahin; Siziopikou, Kalliopi P; Sotiriou, Christos; Stenzinger, Albrecht; Sughayer, Maher A; Sur, Daniel; Symmans, Fraser; Tanaka, Sunao; Taxter, Timothy; Tejpar, Sabine; Teuwen, Jonas; Thompson, E Aubrey; Tramm, Trine; Tran, William T; van der Laak, Jeroen; van Diest, Paul J; Verghese, Gregory E; Viale, Giuseppe; Vieth, Michael; Wahab, Noorul; Walter, Thomas; Waumans, Yannick; Wen, Hannah Y; Yang, Wentao; Yuan, Yinyin; Adams, Sylvia; Bartlett, John Mark Seaverns; Loibl, Sibylle; Denkert, Carsten; Savas, Peter; Loi, Sherene; Salgado, Roberto; Specht Stovgaard, Elisabeth (Peer reviewed; Journal article, 2023)
      Modern histologic imaging platforms coupled with machine learning methods have provided new opportunities to map the spatial distribution of immune cells in the tumor microenvironment. However, there exists no standardized ...
    • Spatial and temporal axes impact ecology of the gut microbiome in juvenile European lobster (Homarus gammarus) 

      Holt, Corey C.; Van der Giezen, Mark; Daniels, Carly L.; Stentiford, Grant D.; Bass, David (Peer reviewed; Journal article, 2019)
      Microbial communities within the gut can markedly impact host health and fitness. To what extent environmental influences affect the differential distribution of these microbial populations may therefore significantly ...
    • Specific PP2A Catalytic Subunits Are a Prerequisite for Positive Growth Effects in Arabidopsis Co-Cultivated with Azospirillum brasilense and Pseudomonas simiae 

      Averkina, Irina Orestovna; Paponov, Ivan; Lillo, Cathrine (Peer reviewed; Journal article, 2020-12)
      Plant growth-promoting rhizobacteria (PGPR) stimulate plant growth, but the underlying mechanism is poorly understood. In this study, we asked whether PROTEIN PHOSPHATASE 2A (PP2A), a regulatory molecular component of ...
    • Spent coffee grounds anaerobic digestion: Investigating substrate to inoculum ratio and dilute acid thermal pretreatment 

      Semaan, Georgeio; Atelge, M.R.; Dune Cayetano, Roent; Kumar, Gopalakrishnan; Kommedal, Roald (Peer reviewed; Journal article, 2022)
      Spent coffee grounds have the potential of being used in further bioprocesses to produce materials and fuels. In Norway, the relative abundance and ease of collection of this waste substrate make it a candidate for ...
    • Statistical Approaches for Dissolution Profile Comparisons of Metformin Film-Coated Tablets 

      Mitrevska, Ivana; Pejov, Ljupco; Trajkovikj, Stefan; Brezovska, Katerina; Dimitrovska, Aneta; Ugarkovic, Sonja (Peer reviewed; Journal article, 2020)
      The objective of this work was to apply several statistical approaches to profile comparison on dissolution data of Metformin immediate release film-coated tablets to assure that the developed formulation of the test product ...
    • Stochastic simulations as a tool for assessing signal fidelity in gene expression in synthetic promoter design 

      Righetti, Elena; Uluseker, Cansu; Kahramanoğulları, Ozan (Peer reviewed; Journal article, 2021-07)
      The design and development of synthetic biology applications in a workflow often involve connecting modular components. Whereas computer-aided design tools are picking up in synthetic biology as in other areas of engineering, ...
    • Stool Microbiota Diversity Analysis of Blastocystis-Positive and Blastocystis-Negative Individuals 

      Stensvold, Christen Rune; Sørland, Brede Aksdal; Berg, Rebecca P. K. D.; Andersen, Lee O’Brien; van der Giezen, Mark; Bowtell, Joanna L.; El-Badry, Ayman A.; Belkessa, Salem; Kurt, Özgür; Nielsen, Henrik Vedel (Peer reviewed; Journal article, 2022)
      Blastocystis is a unicellular eukaryote found in the gastrointestinal tract of both human and other animal hosts. The clinical significance of colonic Blastocystis colonization remains obscure. In this study, we used ...
    • A strategy to characterize chlorophyll protein interaction in LIL3 

      Mork-Jansson, Astrid Elisabeth; Eichacker, Lutz Andreas (Peer reviewed; Journal article, 2019)
      The function of proteins is at large determined by cofactors selectively bound to protein structure. Without chlorophyll specifically bound to protein, light harvesting and photosynthesis would not be possible. The binding ...
    • Study of the long-finned pilot whale (Globicephala melas) bile content - An indicator of ocean health 

      Pampanin, Daniela Maria; Arnli, William Bossum; Magnuson, Jason Tyler; Monticelli, Giovanna; Dam, Maria; Mikalsen, Svein-Ole; Sydnes, Magne Olav (Peer reviewed; Journal article, 2023)
      Globicephala melas has been harvested in the Faroe Islands for centuries. Given the distances travelled by this species, tissue/body fluid samples represent unique matrices to be considered as an integration of environmental ...
    • Subcellular localization and therapeutic efficacy of polymeric micellar nanoparticles encapsulating bedaquiline for tuberculosis treatment in zebrafish 

      Bhandari, Madhavi; Soria-Carrera, Héctor; Wohlmann, Jens; Dal, Nils-Jørgen; de la Fuente, Jesús M.; Martín-Rapún, Rafael; Griffiths, Gareth Wyn; Fenaroli, Federico (Peer reviewed; Journal article, 2023)
      The combination drug regimens that have long been used to treat tuberculosis (TB), caused by Mycobacterium tuberculosis, are fraught with problems such as frequent administration, long duration of treatment, and harsh ...
    • Substituted Two- To Five-Ring Polycyclic Aromatic Compounds Are Potent Agonists of Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a 

      Lille-Langøy, Roger; Jørgensen, Kåre Bredeli; Goksøyr, Anders; Pampanin, Daniela Maria; Sydnes, Magne Olav; Karlsen, Odd André (Peer reviewed; Journal article, 2021)
      Polycyclic aromatic hydrocarbons (PAHs) are among the most toxic and bioavailable components found in petroleum and represent a high risk to aquatic organisms. The aryl hydrocarbon receptor (Ahr) is a ligand-activated ...
    • Sulfur‐Decorated Ni−N−C Catalyst for Electrocatalytic CO2 Reduction with Near 100 % CO Selectivity 

      Lu, Song; Zhang, Yang; Mady, Mohamed F; Eleri, Obinna Egwu; Tucho, Wakshum Mekonnen; Mazur, Michal; Li, Ang; Lou, Fengliu; Gu, Mingfen; Yu, Zhixin (Peer reviewed; Journal article, 2022-08)
      Developing highly efficient electrocatalysts for electrochemical CO2 reduction (ECR) to value-added products is important for CO2 conversion and utilization technologies. In this work, a sulfur-doped Ni−N−C catalyst is ...
    • Synergistic Gas Hydrate and Corrosion Inhibition Using Maleic Anhydride: N-Isopropylmethacrylamide Copolymer and Small Thiols 

      Pomicpic, Janronel Calog; Kelland, Malcolm Andrew (Peer reviewed; Journal article, 2023)
      Kinetic gas hydrate inhibitors (KHIs) are often used in combination with film-forming corrosion inhibitors (CIs) in oilfield production flow lines. However, CIs can be antagonistic to KHI performance. In this study, maleic ...
    • Synergy Effect Study of Poly(N-isoacrylamide) with Tetra Butyl Phosphonium Bromide on Methane Hydrate Formation 

      Seo, SeongDeok; Paik, Hyun-jong; Kang, KyungChan; Kelland, Malcolm Andrew; Lee, JuDong (Journal article, 2019)
      Natural gas hydrate plugging is one of the costly and challenging problems for the oil and gas industry, especially for subsea fields. One way to prevent gas hydrate formation at low cost is the use of low-dosage hydrate ...
    • Synthesis and Antiscaling Evaluation of Novel Hydroxybisphosphonates for Oilfield Applications 

      Mady, Mohamed Fawzy Hamed Attia; Rehman, Abdur; Kelland, Malcolm Andrew (Peer reviewed; Journal article, 2021)
      Organophosphorous compounds are still widely used as potential scale inhibitors in the upstream oil and gas industry, particularly in squeeze treatments as they have good adsorption properties on rock and are easily ...